Synthesized complex-frequency excitation for ultrasensitive molecular sensing

Kebo Zeng; Chenchen Wu; Xiangdong Guo; Fuxin Guan; Yu Duan; Lauren L. Zhang; Xiaoxia Yang; Na Liu; Qing Dai; Shuang Zhang

doi:10.1186/s43593-023-00058-y

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Synthesized complex-frequency excitation for ultrasensitive molecular sensing

eLight Vol. 4, (2024)

RESEARCH ARTICLE | Updated：2024-09-25

- Synthesized complex-frequency excitation for ultrasensitive molecular sensing
- Affiliations：
  
  New Cornerstone Science Laboratory, Department of Physics, University of Hong Kong, Hong Kong, China
  CAS Key Laboratory of Nanophotonic Materials and Devices, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, China
  Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
  2nd Physics Institute, University of Stuttgart, Pfaffenwaldring 57, 70569Stuttgart, Germany
  Max Planck Institute for Solid State Research, D-70569Stuttgart, Germany
  Department of Electrical and Electronic Engineering, University of Hong Kong, Hong Kong, China
- Author bio：
  
  *Xiaoxia Yangyangxx@nanoctr.cn
  Na Liuna.liu@pi2.uni-stuttgart.de
  Qing Daidaiq@nanoctr.cn
  Shuang Zhangshuzhang@hku.hk
- Funds：
- DOI：10.1186/s43593-023-00058-y
  CLC：
- Received：30 August 2023，
  
  Revised：05 November 2023，
  
  Accepted：2023-11-07，
  
  Published Online：05 January 2024，
  
  Published：2024-12
- Accepted：
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Kebo Zeng, Chenchen Wu, Xiangdong Guo, et al. Synthesized complex-frequency excitation for ultrasensitive molecular sensing[J]. Elight, 2024, 4.
DOI：

Kebo Zeng, Chenchen Wu, Xiangdong Guo, et al. Synthesized complex-frequency excitation for ultrasensitive molecular sensing[J]. Elight, 2024, 4. DOI： 10.1186/s43593-023-00058-y.

摘要

Abstract

Sensors have emerged as indispensable analytical tools across a wide range of important fields

encompassing environmental monitoring

food safety

and public health. They facilitate early disease diagnosis

personalized medicine

and rapid detection of toxic agents. However

detecting trace molecules remains a significant challenge. Surface-enhanced infrared absorption (SEIRA) based on plasmonic nanostructures

particularly graphene

has emerged as a promising approach to enhance sensing sensitivity. While graphene-based SEIRA offers advantages such as high sensitivity and active tunability

intrinsic molecular damping weakens the interaction between vibrational modes and plasmons. Here

we demonstrate ultrahigh-sensitive molecular sensing based on synthesized complex-frequency waves (CFW). Our experiment shows that CFW can amplify the molecular signals (silk protein monolayer) detected by graphene-based sensor by at least an order of magnitude and can be universally applied to molecular sensing in different phases. Our approach is highly scalable and can facilitate the investigation of light-matter interactions

enabling diverse potential applications in fields such as optical spectroscopy

biomedicine and pharmaceutics.

关键词

Keywords

references

D. Rodrigo et al . , Mid-infrared plasmonic biosensing with graphene . Science 349 ( 6244 ), 165 – 168 ( 2015 )

A. Tittl et al . , Imaging-based molecular barcoding with pixelated dielectric metasurfaces . Science 360 ( 6393 ), 1105 – 1109 ( 2018 )

N. Liu et al . , Plasmonic analogue of electromagnetically induced transparency at the Drude damping limit . Nat. Mater . 8 ( 9 ), 758 – 762 ( 2009 )

D. N. Basov , M.M. Fogler , F.J. Garcia de Abajo , Polaritons in van der Waals materials . Science, 354 ( 6309 ), ( 2016 )

R. Chikkaraddy et al . , Single-molecule strong coupling at room temperature in plasmonic nanocavities . Nature 535 ( 7610 ), 127 – 130 ( 2016 )

K.V. Sreekanth et al . , Extreme sensitivity biosensing platform based on hyperbolic metamaterials . Nat. Mater . 15 ( 6 ), 621 – 627 ( 2016 )

J.J. Baumberg et al . , Extreme nanophotonics from ultrathin metallic gaps . Nat. Mater . 18 ( 7 ), 668 – 678 ( 2019 )

S.H. Oh et al . , Nanophotonic biosensors harnessing van der Waals materials . Nat. Commun . 12 ( 1 ), 3824 ( 2021 )

H. Altug et al . , Advances and applications of nanophotonic biosensors . Nat. Nanotechnol . 17 ( 1 ), 5 – 16 ( 2022 )

Y. Li et al . , Graphene plasmon enhanced vibrational sensing of surface-adsorbed layers . Nano Lett . 14 ( 3 ), 1573 – 1577 ( 2014 )

I.H. Lee et al . , Graphene acoustic plasmon resonator for ultrasensitive infrared spectroscopy . Nat. Nanotechnol . 14 ( 4 ), 313 – 319 ( 2019 )

R. Adato , H. Altug , In-situ ultra-sensitive infrared absorption spectroscopy of biomolecule interactions in real time with plasmonic nanoantennas . Nat. Commun . 4 , 2154 ( 2013 )

X. Yang et al . , Nanomaterial-based plasmon-enhanced infrared spectroscopy . Adv. Mater . 30 ( 20 ), e1704896 ( 2018 )

A. John-Herpin et al . , Metasurface-enhanced infrared spectroscopy: an abundance of materials and functionalities . Adv. Mater . 35 , e2110163 ( 2022 )

F.H. Koppens , D.E. Chang , F.J. Garciade Abajo , Graphene plasmonics: a platform for strong light-matter interactions . Nano Lett . 11 ( 8 ), 3370 – 3377 ( 2011 )

T. Low et al . , Polaritons in layered two-dimensional materials . Nat. Mater . 16 ( 2 ), 182 – 194 ( 2017 )

S. Zeng et al . , Nanomaterials enhanced surface plasmon resonance for biological and chemical sensing applications . Chem. Soc. Rev . 43 ( 10 ), 3426 – 3452 ( 2014 )

A. Hartstein , J. Kirtley , J. Tsang , Enhancement of the infrared absorption from molecular monolayers with thin metal overlayers . Phys. Rev. Lett . 45 ( 3 ), 201 ( 1980 )

H. Hu et al . , Gas identification with graphene plasmons . Nat. Commun . 10 ( 1 ), 1131 ( 2019 )

A. Bylinkin et al . , Real-space observation of vibrational strong coupling between propagating phonon polaritons and organic molecules . Nat. Photonics 15 ( 3 ), 197 – 202 ( 2020 )

M. Autore et al . , Boron nitride nanoresonators for phonon-enhanced molecular vibrational spectroscopy at the strong coupling limit . Light Sci. Appl . 7 , 17172 ( 2018 )

C. Wu et al . , Ultrasensitive mid-infrared biosensing in aqueous solutions with graphene plasmons . Adv. Mater . 34 ( 27 ), e2110525 ( 2022 )

Z. Fei et al . , Gate-tuning of graphene plasmons revealed by infrared nano-imaging . Nature 487 ( 7405 ), 82 – 85 ( 2012 )

J. Chen et al . , Optical nano-imaging of gate-tunable graphene plasmons . Nature 487 ( 7405 ), 77 – 81 ( 2012 )

S.A. Ramakrishna , J.B. Pendry , Removal of absorption and increase in resolution in a near-field lens via optical gain . Phys. Rev. B 67 ( 20 ), 201101 ( 2003 )

A. Fang et al . , Self-consistent calculation of metamaterials with gain . Phys. Rev. B 79 ( 24 ), 241104 ( 2009 )

J. Grgić et al . , Fundamental limitations to gain enhancement in periodic media and waveguides . Phys. Rev. Lett . 108 ( 18 ), 183903 ( 2012 )

M.I. Stockman , Spaser action, loss compensation, and stability in plasmonic systems with gain . Phys. Rev. Lett . 106 ( 15 ), 156802 ( 2011 )

J. Pendry , S. Maier , Comment on “Spaser action, loss compensation, and stability in plasmonic systems with gain.” Phys . Rev. Lett . 107 ( 25 ), 259703 ( 2011 )

A. Archambault , M. Besbes , J.-J. Greffet , Superlens in the time domain . Phys. Rev. Lett . 109 ( 9 ), 097405 ( 2012 )

D.G. Baranov , A. Krasnok , A. Alù , Coherent virtual absorption based on complex zero excitation for ideal light capturing . Optica 4 ( 12 ), 1457 ( 2017 )

H. Li et al . , Virtual parity-time symmetry . Phys. Rev. Lett . 124 ( 19 ), 193901 ( 2020 )

H.S. Tetikol , M.I. Aksun , Enhancement of resolution and propagation length by sources with temporal decay in plasmonic devices . Plasmonics 15 ( 6 ), 2137 – 2146 ( 2020 )

S. Kim et al . , Beyond bounds on light scattering with complex frequency excitations . Phys. Rev. Lett . 129 ( 20 ), 203601 ( 2022 )

Kim, S. , et al . , Loss Compensation and Superresolution in Metamaterials with Excitations at Complex Frequencies . Phys. Rev. X . 13 ( 4 ), 041024 ( 2023 )

Guan, F. , et al . , Overcoming losses in superlenses with synthetic waves of complex frequency . Science . 381 ( 6659 ), 766 – 771 ( 2023 )

G. Zheng et al . , Metasurface holograms reaching 80% efficiency . Nat. Nanotechnol . 10 ( 4 ), 308 – 312 ( 2015 )

B. Gralak et al . , Phase retrieval of reflection and transmission coefficients from Kramers-Kronig relations . J. Opt. Soc. Am. A 32 ( 3 ), 456 – 462 ( 2015 )

P.-Y. Chen , A. Alu , Atomically thin surface cloak using graphene monolayers . ACS Nano 5 ( 7 ), 5855 – 5863 ( 2011 )

X. Guo et al . , Efficient all-optical plasmonic modulators with atomically thin van der Waals heterostructures . Adv. Mater . 32 ( 11 ), e1907105 ( 2020 )

X. Guo et al . , Higher order Fano graphene metamaterials for nanoscale optical sensing . Nanoscale 9 ( 39 ), 14998 – 15004 ( 2017 )

X. Yang et al . , Nanomaterial-based plasmon-enhanced infrared spectroscopy . Adv. Mater . 30 ( 20 ), 1704896 ( 2018 )

H. Yan et al . , Tunable phonon-induced transparency in bilayer graphene nanoribbons . Nano Lett . 14 ( 8 ), 4581 – 4586 ( 2014 )

U. Fano , Effects of configuration interaction on intensities and phase shifts . Phys. Rev . 124 ( 6 ), 1866 ( 1961 )

I. Greving et al . , Shear-induced self-assembly of native silk proteins into fibrils studied by atomic force microscopy . Biomacromol 13 ( 3 ), 676 – 682 ( 2012 )

D. Eliaz et al . , Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers . Nat. Commun . 13 ( 1 ), 7856 ( 2022 )

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